Ace the CRNI Challenge 2026 – Infuse Your Career with Success!

Monitoring BUN (blood urea nitrogen) and creatinine levels is essential during the infusion of pentamidine due to the drug's potential nephrotoxicity. Pentamidine can lead to renal impairment, which can manifest as increased levels of BUN and creatinine in the blood. Regularly assessing these levels helps to identify any adverse effects on kidney function early, allowing for timely intervention to mitigate potential damage. Thus, this monitoring protocol is a key aspect of patient safety and effective management when administering pentamidine.

In contrast, administering bolus doses may not be the appropriate method for this medication as pentamidine is usually infused over a longer period to reduce complications. A rapid infusion can increase the risk of adverse reactions, and zero hydration might not adequately prevent renal toxicity, particularly in patients who may already be at risk. Therefore, consistent monitoring of renal function represents a critical practice when infusing pentamidine.