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Which antiviral medication is commonly used when CMV strains exhibit resistance?

Foscarnet

The antiviral medication that is commonly used when cytomegalovirus (CMV) strains exhibit resistance is Foscarnet. Foscarnet is particularly effective against resistant strains of CMV that do not respond to Ganciclovir, which is often the first-line treatment for CMV infections.

Foscarnet works by inhibiting viral DNA polymerase, thus disrupting the replication of the virus. It has a different mechanism of action compared to Ganciclovir and is often reserved for cases where other medications fail due to resistance.

Ganciclovir and Cytovene refer to the same drug, with Ganciclovir being the generic name and Cytovene being the brand name. While it is effective against CMV infections, resistance can occur, and in those cases, Foscarnet becomes the preferred choice for treatment.

Acyclovir, while an antiviral medication, primarily treats herpes simplex virus and varicella-zoster virus infections, and is not typically used for CMV. Understanding the use of Foscarnet in the context of resistant CMV strains highlights its importance in managing complex viral infections.

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Cytovene

Ganciclovir

Acyclovir

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